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hsd17b3

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Official Full Name
hydroxysteroid (17-beta) dehydrogenase 3
Background
This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone.It preferentially uses NADP as cofactor.Deficiency can result in male pseudohermaphroditism with gynecomastia.
Synonyms
HSD17B3; hydroxysteroid (17-beta) dehydrogenase 3; testosterone 17-beta-dehydrogenase 3; SDR12C2; short chain dehydrogenase/reductase family 12C; member 2; 17 @beta HSD III; 17 beta HSD 3; 17-@beta hydroxysteroid dehydrogenase III; 17-beta-hydroxysteroid dehydrogenase type 3; EC 1.1.1.64; EDH17B3; Estradiol 17 beta dehydrogenase; Estradiol 17 beta dehydrogenase 3; Hydroxysteroid (17 beta) dehydrogenase 3; OTTHUMP00000021718; Testicular 17 @beta hydroxysteroid dehydrogenaseIII; Testicular 17 beta hydroxysteroid dehydrogenase; Testosterone 17 beta dehydrogenase 3; 17-beta-HSD3; 17-beta-HSD 3; testicular 17-beta-hydroxysteroid dehydrogenase; short chain dehydrogenase/reductase family 12C, member 2; zgc:64019