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hpr

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Official Full Name
haptoglobin-related protein
Background
This gene encodes a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer.
Synonyms
HPR; haptoglobin-related protein; Haptoglobin related locus; haptoglobin related protein; HP; Haptoglobin-related locus; A-259H10.2

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