This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC5, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5 non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants have been described for HOXC5. The transcript variant which includes the shared exon apparently doesnt encode a protein. The protein-coding transcript variant contains gene-specific exons only.
HOXC5; homeobox C5; homeo box C5 , HOX3, HOX3D; homeobox protein Hox-C5; CP11; homeo box C5; Homeobox protein CP11; homeobox protein Hox C5; Homeobox protein Hox-3D; Hox 3D; HOX3; HOX3D; HXC5_HUMAN; OTTHUMP00000217386