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hoxb5

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Official Full Name
homeobox B5
Background
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue.
Synonyms
HOXB5; homeobox B5; homeo box B5 , HOX2, HOX2A; homeobox protein Hox-B5; HGNC:5116; HHO.C10; Homeo box 2A; Homeo box B5; Homeobox 2A; Homeobox protein HHO.C10; Homeobox protein Hox B5; Homeobox protein Hox-2A; Homeobox protein HoxB5; Homeobox protein Hu-1; Homeobox2A; HomeoboxB5; HOX 2; Hox 2.1; HOX 2A; HOX B5; HOX2; Hox2.1; HOX2A; HOXB 5; HU 1; HU1; HXB5_HUMAN; HU-1; HOX2, HU-1, HOX2A, Hox2.1, HHO.C10; Hoxb-5; Ghox-2.1; homeobox protein Hox-2.1