This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML).
HOXB3; homeobox B3; homeo box B3 , HOX2, HOX2G; homeobox protein Hox-B3; Homeo box 2G; Homeo box B3; Homeobox protein Hox-2.7; Homeobox protein Hox-2G; Homeobox protein HoxB3; Hox 2.7; HOX 2G; HOX2; Hox2.7; HOX2G; HXB3_HUMAN; Hox-2.7; 2.7; CHOX; HOXB-3; chox-2.7