In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis. Read-through transcription exists between this gene and the upstream homeobox A10 (HOXA10) gene.
HOXA9; homeobox A9; homeo box A9 , HOX1, HOX1G; homeobox protein Hox-A9; ABD-B; Abd-B, drosophila, homolog of; D6a9; Homeobox 1G; Homeobox protein Hox-1.7; Homeobox protein Hox-1G; Hox-1.7; Hox-1.7, mouse, homolog of; HOX1; Hox1.7; Hox1G; Hox1r5; Hoxa-9; Hoxa7; HOXA9/MSI2 fusion gene, included; HOXA9/NUP98 fusion gene, included; MGC1934; OTTHUMP00000217260; homeodomain protein HOXA9