In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome.
HOXA13; homeobox A13; homeo box A13 , HOX1, HOX1J; homeobox protein Hox-A13; Homeo box 1J; Homeo box A13; Homeobox 1J; Homeobox protein Hox A13; Homeobox protein Hox-1J; Homeobox protein HOXA13; Homeobox1J; HomeoboxA13; HOX 1; HOX 1J; Hox 1J protein; HOX A13; HOX1; HOX1J; HOXA 13; HXA13_HUMAN; Transcription factor HOXA13; OTTHUMP00000217287; HOX protein