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hoxa11

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Official Full Name
homeobox A11
Background
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia. [provided by RefSeq, Jul 2008]
Synonyms
HOXA11; homeobox A11; HOX1; HOX1I; homeobox protein Hox-A11; homeo box 1I; homeobox protein HOXA11; homeobox protein Hox-1I; GHOX1I; ghox-1I; chox-1.9; homeo box A11; homeobox protein Hox-1.9; homeodomain-containing protein