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hgf

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Official Full Name
son of sevenless homolog 1 (Drosophila)
Background
This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008]
Synonyms
SOS1; son of sevenless homolog 1 (Drosophila); GF1; HGF; NS4; GGF1; GINGF; son of sevenless homolog 1; SOS-1; guanine nucleotide exchange factor; gingival fibromatosis, hereditary, 1; fj59e07; wu:fj59e07; zgc:158274; son of sevenless homolog