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hdac7

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Official Full Name
histone deacetylase 7
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
HDAC7; histone deacetylase 7; HD7A; HDAC7A; HD7; histone deacetylase 7A; HDAC7A, histone deacetylase 7A; DKFZP586J0917; FLJ99588