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hdac1

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Official Full Name
histone deacetylase 1
Background
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]
Synonyms
HDAC1; histone deacetylase 1; HD1; RPD3; GON-10; RPD3L1; reduced potassium dependency, yeast homolog-like 1; GON 10; DKFZp686H12203; hdac-1; chunp6919; zgc:65818; wu:fb19h11; wu:fi06f03; zgc:101582; mp:zf637-2-001987; col; colgate