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Official Full Name
hypocretin (orexin) neuropeptide precursor
Background
This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis.
Synonyms
HCRT; hypocretin (orexin) neuropeptide precursor; orexin; OX; PPOX; Hcrt2; Hypocretin 2; hypocretin; NRCLP1; Orexin precursor; prepro orexin; hypocretin (orexin) neuropeptide; hypocretin/orexin

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