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gzma

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Official Full Name
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
Background
Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface nonself antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. [provided by RefSeq, Jul 2008]
Synonyms
GZMA; granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3); HFSP; CTLA3; granzyme A; HF; h factor; CTL tryptase; fragmentin-1; cytotoxic T-lymphocyte proteinase 1; Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3; Hanukah factor serine protease); CTLA3, HFSP; Granzyme A (Cytotoxic T lymphocyte associated serine esterase 3