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gtf3c6

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Official Full Name
general transcription factor IIIC, polypeptide 6, alpha 35kDa
Background
RNA polymerases are unable to initiate RNA synthesis in the absence of additional proteins called general transcription factors (GTFs). GTFs assemble in a complex on the DNA promoter and recruit the RNA polymerase. GTF3C family proteins (e.g., GTF3C1, MIM 603246) are essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA (MIM 180420), tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin.
Synonyms
GTF3C6; general transcription factor IIIC, polypeptide 6, alpha 35kDa; C6orf51, chromosome 6 open reading frame 51; general transcription factor 3C polypeptide 6; bA397G5.3; TFIIIC35; C6ORF51; General transcription factor IIIC polypeptide 6 alpha; TF3C6_HUMAN; TFIIIC 35 kDa subunit; Transcription factor IIIC 35 kDa subunit; Transcription factor IIIC 35kDa; Transcription factor IIIC polypeptide 6; Transcription factor IIIC subunit 6; general transcription factor IIIC, polypeptide 6, alpha; zgc:56388

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