The human Transcription Factor IIE (TFIIE) is composed of 56 kDa (alpha) and 34 kDa (beta) subunits and is shown to be a heterotetramer. The 56 kDa subunit contains a region similar to a zinc-binding domain and a region sharing homology with the catalytic loop of a kinase domain. TFIIE binds to RNA polymerase II in solution and joins the preinitiation complex probably concomitant with RNA polymerase II and TFIIF. alpha-TFIIE beta is an af?nity-puri?ed rabbit polyclonal antibody raised against a recombinant full-length p34 subunit of the TFIIE complex.
GTF2E2; general transcription factor IIE, polypeptide 2, beta 34kDa; general transcription factor IIE, polypeptide 2 (beta subunit, 34kD); transcription initiation factor IIE subunit beta; FE; TF2E2; TFIIE B; TFIIE-beta; general transcription factor IIE subunit 2; TFIIE-B; general transcription factor IIE, polypeptide 2, beta; zgc:77074; wu:fa05d01