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gsn

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Official Full Name
gelsolin
Background
The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
GSN; gelsolin; ADF; AGEL; brevin; actin-depolymerizing factor; homogenin