Official Full Name
G protein-coupled receptor kinase 1
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2).
GRK1; G protein-coupled receptor kinase 1; rhodopsin kinase , RHOK; rhodopsin kinase; GPRK1; RK; RHOK; G-protein coupled receptor kinase 1