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grik3

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Official Full Name
glutamate receptor, ionotropic, kainate 3
Background
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.
Synonyms
GRIK3; glutamate receptor, ionotropic, kainate 3; glutamate receptor, ionotropic kainate 3; GLUR7; EAA5; Excitatory amino acid receptor 5; GLR 7; GLR7; GLU R7; GLUR 7; GluR 7a; GluR7a; Glutamate receptor 7; Glutamate receptor ionotropic kainate 3; GRIK 3; gluR-7; dJ1090M5.1 (glutamate receptor, ionotropic, kainate 3 (GLUR7))