G-protein signaling modulators (GPSM) play diverse functional roles through their interaction with G-protein subunits. This gene encodes a receptor-independent activator of G protein signaling, which is one of several factors that influence the basal activity of G protein signaling systems. The protein contains seven tetratricopeptide repeats in its N-terminal half and four G-protein regulatory (GPR) motifs in its C-terminal half. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
GPSM1; G-protein signaling modulator 1; G protein signalling modulator 1 (AGS3 like, C. elegans); G-protein-signaling modulator 1; AGS3; AGS3 homolog (C. elegans); DKFZP727I051; Activator of G-protein signaling 3; AGS3 homolog; C10a; G protein signaling modulator 1 (AGS3 like, C. elegans); GPSM1_HUMAN; 1810037C22Rik; G-protein signaling modulator 1 (AGS3-like, C. elegans); G-protein signalling modulator 1 (AGS3-like, C. elegans)