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gpld1

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Official Full Name
glycosylphosphatidylinositol specific phospholipase D1
Background
Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane. [provided by RefSeq, Jul 2008]
Synonyms
GPLD1; glycosylphosphatidylinositol specific phospholipase D1; PLD; GPIPLD; PIGPLD; GPIPLDM; PIGPLD1; phosphatidylinositol-glycan-specific phospholipase D; GPI-PLD; PI-G PLD; GPI-specific phospholipase D; glycoprotein phospholipase D; glycosylphosphatidylinositol specific phospholipase D1, isoform 2; phospholipase D, phosphatidylinositol-glycan-specific; MGC22590