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gls

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Official Full Name
glutaminase
Background
This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase;that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain;and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter;glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants.
Synonyms
GLS; glutaminase; AI314027; 6330442B14; B230365M23Rik; glutaminase kidney isoform, mitochondrial; glutaminase C