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Official Full Name
gastric intrinsic factor (vitamin B synthesis)
Background
Intrinsic factor promotes absorption of the essential vitamin Cobalamin (Cbl) in the ileum by specific receptor mediated endocytosis. Defects in the gene GIF are the cause of hereditary intrinsic factor deficiency (IFD) also called congenital pernicious anemia. IFD is an autosomal recessive disorder characterized by megaloblastic anemia.
Synonyms
Gastric Intrinsic Factor; Gastric intrinsic factor (vitamin B synthesis); GIF; IF; IFMH; INF; Intrinsic factor; TCM3; TCN3; Intrinsic Factor Ab