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gga2

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Official Full Name
golgi-associated, gamma adaptin ear containing, ARF binding protein 2
Background
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly.
Synonyms
GGA2; golgi-associated, gamma adaptin ear containing, ARF binding protein 2; ADP-ribosylation factor-binding protein GGA2; KIAA1080; VEAR; ARF-binding protein 2; gamma ear-containing; 1200007E24Rik; ADP ribosylation factor binding protein 2; ADP ribosylation factor binding protein GGA 2; ADP ribosylation factor binding protein GGA2; FLJ20966; Gamma adaptin related protein 2; Gamma-adaptin related protein 2; Gamma-adaptin-related protein 2; GGA 2; GGA2_HUMAN; Golgi associated gamma adaptin ear containing ARF binding protein 2; Golgi localized gamma ear containing ARF binding protein 2; Golgi-localized; VHS domain and ear domain containing protein; VHS domain and ear domain of gamma adaptin; VHS domain and ear domain of gamma-adaptin; VHS domain and ear domain-containing protein; golgi-localized, gamma ear-containing, ARF-binding protein 2; golgi associated, gamma adaptin ear containing, ARF binding protein 2