This locus represents naturally occurring readthrough transcription between the neighboring MYZAP (myocardial zonula adherens protein) and POLR2M (polymerase (RNA) II (DNA directed) polypeptide M) genes on chromosome 15. Alternate splicing results in two readthrough transcript variants that encode different isoforms. One of the readthrough variants encodes a fusion protein that shares sequence identity with each individual gene product. The other variant encodes a protein that shares sequence identity with the upstream gene product but its C-terminal region is distinct due to frameshifts relative to the downstream gene.
GCOM1; GRINL1A complex locus 1; GRINL1A combined protein; FLJ30973; GRINL1A; MYZAP POLR2M; MYZAP POLR2M readthrough; Gcom2; Glutamate receptor ionotropic N methyl D aspartate like 1A combined; GRINL1A combined protein Gcom12; GRINL1A upstream protein; Gup1; Gup2; MGC126694; MGC138353; NMDAR1 subunit interacting protein; OTTHUMP00000163287; MYZAP-POLR2M protein; MYZAP-POLR2M readthrough; GRINL1A complex locus protein 1; NMDAR1 subunit-interacting protein; glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A combined protein; gcom; MYZAP-POLR2M