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gchfr

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Official Full Name
GTP cyclohydrolase I feedback regulator
Background
GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide.
Synonyms
GCHFR; GTP cyclohydrolase I feedback regulator; GTP cyclohydrolase I feedback regulatory protein; GTP cyclohydrolase 1 feedback regulatory protein; GFRP; HsT16933; GFRP_HUMAN; MGC138467; MGC138469; p35; OTTHUMP00000160546; zgc:73253