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gcdh

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Official Full Name
glutaryl-CoA dehydrogenase
Background
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms
GCDH; glutaryl-CoA dehydrogenase; glutaryl Coenzyme A dehydrogenase; glutaryl-CoA dehydrogenase, mitochondrial; ACAD5; mitochondrial; EC 1.3.99.7; GCD; GCDH_HUMAN; Glutaryl CoA dehydrogenase, mitochondrial; MS781; glutaryl-Coenzyme A dehydrogenase; ACAD5, GCD, GCDH

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