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gas2

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Official Full Name
growth arrest-specific 2
Background
The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Synonyms
GAS2; growth arrest-specific 2; growth arrest-specific protein 2; GAS-2; MGC32610