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gan

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Official Full Name
gigaxonin
Background
This gene encodes a member of the cytoskeletal BTB/kelch (Broad-Complex, Tramtrack and Bric a brac) repeat family. The encoded protein plays a role in neurofilament architecture and is involved in mediating the ubiquitination and degradation of some proteins. Defects in this gene are a cause of giant axonal neuropathy (GAN). [provided by RefSeq, Oct 2008]
Synonyms
GAN; gigaxonin; GAN1; KLHL16; kelch-like protein 16; kelch-like family member 16; giant axonal neuropathy (gigaxonin); FLJ38059

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