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gage1

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Official Full Name
G antigen 1
Background
This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YRPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. Nothing is presently known about the function of this protein. Alternative splicing results in multiple transcript variants.
Synonyms
GAGE1; G antigen 1; cancer/testis antigen family 4; member 1; CT4.1; Cancer/testis antigen 4.1; CT4 1; GAGE 1; MZ2 F antigen; MZ2-F antigen; cancer/testis antigen family 4, member 1; GAGE-1