This gene encodes an enzyme belonging to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternative splicing results in multiple transcript variants.
FUT8; fucosyltransferase 8 (alpha (1,6) fucosyltransferase); alpha-(1,6)-fucosyltransferase; 6)-fucosyltransferase; 6-fucosyltransferase; Alpha (1,6) fucosyltransferase; Alpha-(1; Alpha1 6FucT; alpha1-6FucT; Fucosyltransferase 8; FUT8_HUMAN; GDP fucose glycoprotein fucosyltransferase; GDP L Fuc:N acetyl beta D glucosaminide alpha1,6 fucosyltransferase; GDP-fucose--glycoprotein fucosyltransferase; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1; Glycoprotein 6 alpha L fucosyltransferase; Glycoprotein 6-alpha-L-fucosyltransferase; MGC26465; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase; FUT8 alpha 1,6 fucosyltransferase