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foxo3

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Official Full Name
forkhead box O3
Background
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
Synonyms
FOXO3; forkhead box O3; FOXO2; AF6q21; FKHRL1; FOXO3A; FKHRL1P2; forkhead box protein O3; forkhead box O3A; forkhead in rhabdomyosarcoma-like 1; forkhead homolog (rhabdomyosarcoma) like 1; forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1; FKHRL1, FOXO3A; MGC12739; MGC31925; DKFZp781A0677