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fn3krp

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Official Full Name
fructosamine 3 kinase related protein
Background
A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine;residues (glycation). Proteins modified in this way are less active or functional. This gene encodes an enzyme which;catalyzes the phosphorylation of psicosamines and ribulosamines compared to the neighboring gene which encodes a;highly similar enzyme, fructosamine-3-kinase, which has different substrate specificity. The activity of both enzymes;may result in deglycation of proteins to restore their function. Alternative splicing results in multiple transcript;variants.
Synonyms
FN3KRP; fructosamine 3 kinase related protein; ketosamine-3-kinase; EC 2.7.1.-; FLJ12171; FN3K-related protein; FN3K-RP; FN3KL; Fn3krp fructosamine-3-kinase-related protein; FN3X; Fructosamine-3-kinase-related protein; MGC40640; RGD1304570; RP23-293H17.3; zgc:101634