The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in humans, this enzyme is truncated and is probably rapidly degraded. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1.
FMO2; flavin containing monooxygenase 2 (non-functional); flavin containing monooxygenase 2; dimethylaniline monooxygenase [N-oxide-forming] 2; MGC28212; OTTMUSP00000028687; 2310008D08Rik; 2310042I22Rik; AW107733; Dimethylaniline monooxygenase [N oxide forming] 2; Dimethylaniline oxidase 2; Flavin containing monooxygenase 2 (non functional); FLJ40826; FMO 1B1; FMO 2; FMO; FMO pulmonary; FMO1B1; OTTMUSP00000028686; Pulmonary flavin containing monooxygenase 2; FMO, pulmonary; pulmonary flavin-containing monooxygenase 2; FMO4