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fgfbp1

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Official Full Name
Homo sapiens fibroblast growth factor binding protein 1 DNA.
Background
This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4.
Synonyms
FGFBP1; fibroblast growth factor binding protein 1; fibroblast growth factor-binding protein 1; FGFBP; HBP17; 17 kDa heparin binding growth factor binding protein; FGF binding protein 1; FGF BP; FGF BP1; Fibroblast growth factor binding protein 1 precursor; FGF-binding protein 1; 17 kDa HBGF-binding protein; heparin-binding growth factor binding protein; 17 kDa heparin-binding growth factor-binding protein; FGF-BP; FGF-BP1; FGFBP-1