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fdps

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Official Full Name
farnesyl diphosphate synthase
Background
During blood coagulation, fibrinogen is converted to fibrin by the activation of thrombin. The resulting fibrin monomers polymerize to form a soluble gel of non-cross-linked fibrin. This fibrin gel is then converted to cross-linked fibrin by thrombin activated Factor XIII to form an insoluble fibrin clot. Production of plasmin, the major clot-lysing enzyme, is triggered when a fibrin clot is formed. Fibrinogen and fibrin are both cleaved by the fibrinolytic enzyme plasmin to yield degradation products, but only degradation products from crosslinked fibrin contain D-Dimer. Therefore, cross-linked fibrin degradation products (XL-FDP) are a specific marker of fibrinolysis.
Synonyms
FDPs; Fibrin Degradation Products; Geranyltranstransferase; (2E; 6E)-farnesyl diphosphate synthase; dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl diphosphate synthetase; Farnesyl pyrophosphate synthase; Farnesyl pyrophosphate synthetase; FPP synthase; FPP synthetase; FPPS; FPS; (2E,6E)-farnesyl diphosphate synthase; farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase; farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase); im:6904202; wu:fb23g06; fb23g06