This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least 9 tandem leucine-rich repeats.
FBXL4; F-box and leucine-rich repeat protein 4; F-box/LRR-repeat protein 4; FBL4; FBL5; F box and leucine rich repeat protein 4; F box protein FBL4/FBL5; F box/LRR repeat protein 4; F-box protein FBL 4; F-box protein FBL4/FBL5; FBL 4; FBL 5; FBXL4_HUMAN; F-box protein FBL4; OTTHUMP00000016888; zgc:92297