This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus.
FBXL3; F-box and leucine-rich repeat protein 3; F box and leucine rich repeat protein 3A , FBXL3A; F-box/LRR-repeat protein 3; FBL3; FBL3A; F box and leucine rich repeat protein 3; F box and leucine rich repeat protein 3A; F box protein Fbl3a; FBXL3A; OTTHUMP00000018519; OTTHUMP00000018520; F-box protein Fbl3a; F-box/LRR-repeat protein 3A; F-box and leucine-rich repeat protein 3A