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fabp2

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Official Full Name
fatty acid binding protein 2, intestinal
Background
The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. [provided by RefSeq, Jul 2008]
Synonyms
FABP2; fatty acid binding protein 2, intestinal; FABPI; I-FABP; fatty acid-binding protein, intestinal; fatty acid-binding protein 2; intestinal-type fatty acid-binding protein; I FABP; MGC133132; FABP; intestinal fatty acid-binding protein; ifabp; zgc:92264; I-FABP (FABPI); intestinal fatty acid binding pr; intestinal fatty acid binding protein 2

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