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f2

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Official Full Name
coagulation factor II (thrombin)
Background
Thrombin (activated Factor II [IIa]) is a coagulation protein that has many effects in the coagulation cascade. Thrombin is a serine protease (EC 3.4.21.5) that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions. Thrombin is in the form of alpha-thrombin tat is the immediate end product of prothrombin activation, two further thrombin products can be identified, beta- and gamma-thrombin. These are degraded form that may arise from autodigestion of a thrombin preparation.
Synonyms
F2; coagulation factor II (thrombin); prothrombin; serine protease; prothrombin B-chain; PT; THPH1; thrombin; zgc:66319; wu:fb57c10; wu:fd42e09; wu:fd59d01

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