This gene encodes an endo/exonuclease with 5-3 exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5 end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18.
EXOG; endo/exonuclease (5-3), endonuclease G-like; ENDOGL1, ENDOGL2, endonuclease G like 1 , endonuclease G like 2; nuclease EXOG, mitochondrial; ENGL; ENGL a; ENGL b; endo G-like 1; endonuclease G-like 1; endonuclease G-like 2; ENGLA; ENGLB; ENGL-a; EN; ENGL-b; ENDOGL1; ENDOGL2