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evx2

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Official Full Name
even-skipped homeobox 2
Background
This gene is located at the 5 end of the HOXD gene cluster on chromosome 2. The encoded protein is a homeobox transcription factor that is related to the protein encoded by the Drosophila even-skipped (eve) gene, a member of the pair-rule class of segmentation genes. A 117 kb microdeletion at the 5 end of the HOXD gene cluster, which includes this gene and the HOXD9-HOXD13 genes, causes synpolydactyly, a dominantly inherited disease resulting in limb malformation.
Synonyms
EVX2; eve, even-skipped homeobox homolog 2 (Drosophila); eve, even skipped homeobox homolog 2 (Drosophila); eve, even-skipped homeobox homolog 2; Even-skipped homeo box-2; eve, even-skipped homeo box homolog 2 (Drosophila); even-skipped homeo box 2 (homol; even-skipped homeobox 2; Evx-2; homeobox even-skipped homolog protein 2

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