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eps8l2

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Official Full Name
transaldolase 1
Background
Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis.
Synonyms
TALDO1; transaldolase 1; transaldolase; Dihydroxyacetone transferase; EC 2.2.1.2; EPS8L2; Glycerone transferase; TAL; TAL H; TALDO; TALDOR; TALH; TAL-H; EPS8-like 2; zgc:56232; zgc:66054; wu:fc32g02