Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. May be required for transcriptional activation of E2F1 and MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. May regulate ZNF42 transcription activity.
EP400; E1A binding protein p400; Rabbit; Human; Rabbit Anti-Human EP400 Polyclonal Antibody; Rabbit Anti-Human EP400; Polyclonal Antibody; Rabbit Anti-Human EP400 Antibody; Polyclonal; Rabbit Anti-Human EP400 Polyclonal; Antibody; Rabbit Anti-Human E1A binding protein p400 Antibody; Rabbit Anti-Human E1A binding protein p400 Polyclonal; Anti-Human EP400 Antibody; Anti-Human EP400 Polyclonal; Anti-Human E1A binding protein p400 Antibody; Anti-Human E1A binding protein p400 Polyclonal; Anti-Human EP400; Anti-EP400; Anti-Human E1A binding protein p400; Anti-E1A binding protein p400; TNRC12, trinucleotide repeat containing 12; E1A-binding protein p400; CAGH32; DKFZP434I225; KIAA1498; KIAA1818; P400; hDomino; domino homolog; CAG repeat protein 32; p400 SWI2/SNF2-related protein; p400 kDa SWI2/SNF2-related protein; trinucleotide repeat containing 12; trinucleotide repeat-containing gene 12 protein; TNRC12; FLJ42018; FLJ45115; NOC4L; nucleolar complex protein 4 homolog; NOC4-like protein; NOC4 protein homolog; nucleolar complex-associated protein 4-like protein