This gene encodes a member of the apyrase protein family. Apyrases are enzymes that catalyze the hydrolysis of nucleotide diphosphates and triphosphates in a calcium or magnesium-dependent manner. The encoded protein is an endo-apyrase and may play a role in salvaging nucleotides from lysosomes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and these isoforms may differ in divalent cation dependence and substrate specificity.
ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4; LYSAL1, lysosomal apyrase like 1; KIAA0392; LALP70; LAP70; NTPDase 4; UDPase; Apyrase lysosomal; ENTPD 4; Guanosine diphosphatase like protein; LYSAL1; Lysosomal apyrase like 1; Lysosomal apyrase like protein of 70 kDa; Uridine diphosphatase; golgi luminal UDPase; uridine-diphosphatase; lysosomal apyrase-like 1; guanosine-diphosphatase like protein; lysosomal apyrase-like protein of 70 kDa; NTPDase-4; LAP70, LALP70, LYSAL1, UDPase, NTPDase-4; zgc:92668; wu:fd44h12; wu:fi73e02; NTPDase4