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enosf1

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Official Full Name
enolase superfamily member 1
Background
This gene was originally identified as a naturally occurring antisense transcript to the human thymidylate synthase gene. Alternate splice variants have been described, one of which (named rTSalpha) represents an alternate 3UTR that is complementary to the 3UTR and terminal intron of the thymidylate synthase (TS) RNA and down-regulates TS expression. Other transcript variants (rTSbeta and rTSgamma) do not overlap the TS locus. The function of this gene appears to be primarily to regulate expression of the TS locus both via the antisense transcript as well as through the encoded proteins.
Synonyms
ENOSF1; enolase superfamily member 1; mitochondrial enolase superfamily member 1; HSRTSBETA; rTS; TYMSAS; ENOSF 1; RTS alpha; RTS beta; RTS beta protein; antisense RNA to thymidylate synthase; im:6897724; zgc:153148