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emr2

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Official Full Name
egf-like module containing, mucin-like, hormone receptor-like 2
Background
This gene encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 3 on chromosome 19. This protein does not interact with the ligand decay accelerating factor for complement, unlike the related CD97 antigen, and indicates that these very closely related proteins likely have nonredundant functions. This gene results in multiple transcripts encoding distinct isoforms.
Synonyms
EMR2; egf-like module containing, mucin-like, hormone receptor-like 2; egf like module containing, mucin like, hormone receptor like sequence 2; EGF-like module-containing mucin-like hormone receptor-like 2; CD312; EGF-like module receptor 2; egf-like mod; egf-like module containing, mucin-like, hormone receptor-like sequence 2; DKFZp781B135

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