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ela1

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Official Full Name
Ela1p
Background
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six;elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other;elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 expression has only been;detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas or fecal;material is actually referring to chymotrypsin-like elastase family, member 3B.
Synonyms
ELA1; Ela1p; Elo A; EloA; ELOA1_HUMAN; Elongin 110 kDa subunit; Elongin-A; ElonginA; RNA polymerase II transcription factor SIII subunit A1; SIII; SIII p110; TCEB 3; Tceb3; TCEB3A; Transcription elongation factor B (SIII) polypeptide 3 (110kD); Transcription elongation factor B (SIII) polypeptide 3; Transcription elongation factor B alpha subunit; Transcription elongation factor B polypeptide 3; Elongin A, F-box protein that forms a heterodimer with Elc1p and is required for ubiquitin-dependent degredation of the RNA Polymerase II subunit RPO21; subunit of the Elongin-Cullin-Socs (ECS) ligase complex