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eif4e

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Official Full Name
eukaryotic translation initiation factor 4E
Background
Its translation stimulation activity is repressed by binding to the complex CYFIP1-FMR1 (By similarity). Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.
Synonyms
EIF4E; eukaryotic translation initiation factor 4E; CBP; EIF4F; EIF4E1; EIF4EL1; MGC111573; eIF-4E; OTTHUMP00000219701; OTTHUMP00000219702; OTTHUMP00000219703; OTTHUMP00000219704; OTTHUMP00000219705; eIF-4F 25 kDa subunit; mRNA cap-binding protein; eukaryotic translation initiation factor 4E-like 1; EIF4EL1, EIF4F