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eif2b3

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Official Full Name
eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
Background
The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Synonyms
EIF2B3; eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa; EIF-2B; EIF2Bgamma; translation initiation factor eIF-2B subunit gamma; eIF-2B GDP-GTP exchange factor subunit gamma; eukaryotic translation initiation factor 2B, subunit 3 (gamma, 58kD); EIF 2B; eukaryotic translation initiation factor 2B, subunit 3 gamma; zgc:56473