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egln2

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Official Full Name
egl-9 family hypoxia-inducible factor 2
Background
The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene. [provided by RefSeq, Feb 2011]
Synonyms
EGLN2; egl-9 family hypoxia-inducible factor 2; EIT6; PHD1; HPH-1; HPH-3; HIFPH1; HIF-PH1; egl nine homolog 2; estrogen-induced tag 6; HIF-prolyl hydroxylase 1; hypoxia-inducible factor prolyl hydroxylase 1; prolyl hydroxylase domain-containing protein 1; egl nine homolog 2 (C. elegans); EGL nine (C.elegans) homolog 2; HIF prolyl hydroxylase 1; FLJ95603; DKFZp434E026; EIT6, PHD1, HPH-1, HPH-3, HIFPH1, HIF-PH1